Adipose recruitment and activation of plasmacytoid dendritic cells fuel metaflammation

【Author】

Amrit Raj Ghosh;Roopkatha Bhattacharya;Titli Nargis;Shamik Bhattacharya;Oindrila Rahaman;Pritam Duttagupta;Deblina Raychaudhuri;Chinky Shiu Chen Liu;Shounak Roy;Parasar Ghosh;Shashi Khanna;Tamonas Chaudhuri;Om Tantia;Stefan Haak;Santu Bandyopadhyay;Satinath Mukhopadhyay;Partha Chakrabarti;Dipyaman Ganguly;

【Abstract】

<正>Infiltrating immune cells in the adipose tissue(metaflammation),in addition to deregulated lipogenesis and adipokine expression,has been linked to metabolic syndrome in obesity.We now find that deregulation of a specific adipokine,chemerin may be involved in the initiation of this inflammatory milieu.We found obesity associated overexpression of Chemerin in the visceral adipose tissue(VAT)recruits plasmacytoid dendritic cells(p DCs)into the visceral adipose

【Keywords】

adipose;visceral;obesity;obese;initiation;macrophages;glycation;innate;chemokine;links;

References

To explore the background and basis of the node document

Springer Journals Database

Total: 0 articles

Similar documents

Documents that have the similar content to the node document

Springer Journals Database

Total: 0 articles