A rational media design approach toward the development of a xeno-serum free monocyte-derived dendritic cell medium


William Kim;


<正>Dendritic Cells(DCs)have been well established as"professional"antigen-presenting cells uniquely equipped for controlling both immunity and immune tolerance.Due to their central role in mediating the adaptive immune response and their ability to be manipulated in vitro at therapeutically relevant quantities,monocyte-derived DCs(Mo-DCs)have garnered much attention over the past 15 years in the efforts to develop effective strategies for therapeutic immunity




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