Lenalidomide enhances the function of dendritic cells generated from patients with multiple myeloma

【Author】

Manh-Cuong Vo;Truc Anh Nguyen Thi;Hyun-Ju Lee;Thanh-Nhan Nguyen-Pharm;My-Dung Hoang;Nuri Choi;Sung-Hoon Jung;Hyeoung-Joon Kim;Je-Jung Lee;

【Abstract】

<正>Lenalidomide(LEN)has been used as an immunomodulatory drug with direct and indirect anti-tumor effects.In this study,we evaluated the effect of LEN on the differentiation,maturation,and function of dendritic cells(DCs)in patients with multiple myeloma(MM)in vitro.Various doses of LEN were added after the monocytes had differentiated into immature DCs(im DCs)and activated into mature

【Keywords】

myeloma;mature;maturation;differentiated;indirect;doses;suppressor;interleukin;generating;inducing;

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