An effective cytokine adjuvant vaccine recruits DC and activates autologous T-cell against colon cancer in an animal model

【Author】

huanyu ju;wenjing xing;jinfeng yang;yang zheng;xiuzhi jia;benning zhang;huan ren;

【Abstract】

<正>Background:Despite recent advances in early detection and improvements in chemotherapy for colon cancer,the patients still face poor prognosis of postoperative recurrence and metastasis.Some immunotherapeutic approaches had been attempted in colon cancer patients to significantly increase overall survival.A vaccine based approach has shown a novel direction for colon cancer prevention and therapy.

【Keywords】

colon;vaccine;cytokine;recurrence;metastasis;prognosis;postoperative;chemotherapy;adjuvant;prevention;

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