Glial Activation,A Common Mechanism Underlying Spinal Synaptic Plasticity?

【Author】

Li-Jun Zhou;Xian-Guo Liu;Department of Physiology and Pain Research Center,Zhongshan School of Medicine,Sun Yat-Sen University;

【Institution】

Department of Physiology and Pain Research Center,Zhongshan School of Medicine,Sun Yat-Sen University;

【Abstract】

<正>Long-term potentiation(LTP)at synapses between primary afferents and spinal dorsal horn neurons induced by noxious electrical stimulation or injury of peripheral nerve is considered to underlie chronic pain[1].The mechanisms of the spinal LTP have been intensively investigated,since it was discovered in 1995[2].In recent years,spinal application of

【Keywords】

HFS;LTP;Glial Activation,A Common Mechanism Underlying Spinal Synaptic Plasticity;

References

To explore the background and basis of the node document

Springer Journals Database

Total: 12 articles

  • [1] Yan-Ling Liu;;Li-Jun Zhou;;Neng-Wei Hu;;Ji-Tian Xu;;Chang-You Wu;;Tong Zhang;;Yong-Yong Li;;Xian-Guo Liu, Tumor necrosis factor-α induces long-term potentiation of C-fiber evoked field potentials in spinal dorsal horn in rats with nerve injury: The role of NF-kappa B, JNK and p38 MAPK, Neuropharmacology,
  • [2] Qing-Juan Gong;;Yu-Ying Li;;Wen-Jun Xin;;Xu-Hong Wei;;Yue Cui;;Jun Wang;;Yong Liu;;Cui-Cui Liu;;Yong-Yong Li;;Xian-Guo Liu, Differential effects of adenosine A1 receptor on pain-related behavior in normal and nerve-injured rats, Brain Research,
  • [3] Bo Ying;;Ning Lü;;Yu-Qiu Zhang;;Zhi-Qi Zhao, Involvement of spinal glia in tetanically sciatic stimulation-induced bilateral mechanical allodynia in rats, Biochemical and Biophysical Research Communications,
  • [4] Li-Jun Zhou;;Tao Yang;;Xiao Wei;;Yong Liu;;Wen-Jun Xin;;Yuan Chen;;Rui-Ping Pang;;Ying Zang;;Yong-Yong Li;;Xian-Guo Liu, Brain-derived neurotrophic factor contributes to spinal long-term potentiation and mechanical hypersensitivity by activation of spinal microglia in rat, Brain Behavior and Immunity,

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