Therapeutic Potential of Glucagon-Like Peptide-1 Cleavage Product for Alzheimer's Disease

【Author】

Stephen M.Day;Tao Ma;Department of Internal Medicine, Gerontology and Geriatric Medicine, Wake Forest School of Medicine;Department of Physiology and Pharmacology, Wake Forest School of Medicine;Department of Neurobiology and Anatomy, Wake Forest School of Medicine;

【Institution】

Department of Internal Medicine, Gerontology and Geriatric Medicine, Wake Forest School of Medicine;Department of Physiology and Pharmacology, Wake Forest School of Medicine;Department of Neurobiology and Anatomy, Wake Forest School of Medicine;

【Abstract】

<正>Alzheimer’s disease (AD) is a devastating neurodegenerative disease and the most common form of dementia in the elderly. Concurrent with an aging population, the incidence of AD has been rising steadily and become a global threat to public health [1]. Unfortunately, there are currently no effective interventions that can cure AD or slow its progression, and recently finished clinical trials targeting

【Keywords】

GLP;Therapeutic Potential of Glucagon-Like Peptide-1 Cleavage Product for Alzheimer's Disease;Alzheimer;

References

To explore the background and basis of the node document

Springer Journals Database

Total: 8 articles

  • [1] Christian Hlscher;Biomedical and Life Sciences, Lancaster University;, Drugs developed for treatment of diabetes show protective effects in Alzheimer's and Parkinson's diseases, Acta Physiologica Sinica,
  • [2] Dema Najem;Michelle Bamji-Mirza;Ze Yang;Wandong Zhang;Faculty of Medicine,University of Ottawa;Human Health Therapeutics,National Research Council of Canada;Beijing Hospital,Institute of Geriatrics-Chinese Health Ministry;, Ab-Induced Insulin Resistance and the Effects of Insulin on the Cholesterol Synthesis Pathway and Ab Secretion in Neural Cells, Neuroscience Bulletin,
  • [3] Laurie L. Baggio;;Daniel J. Drucker, Biology of Incretins: GLP-1 and GIP, Gastroenterology,
  • [4] GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid, European Journal of Pharmacology,

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