MicroRNA21 Meets Neuronal TLR8: Non-canonical Functions of MicroRNA in Neuropathic Pain

【Author】

Zhi-Hong Wang;Tong Liu;Jiangsu Key Laboratory of Neuropsychiatric Diseases and Institute of Neuroscience, Soochow University;College of Life Sciences, Yanan University;

【Institution】

Jiangsu Key Laboratory of Neuropsychiatric Diseases and Institute of Neuroscience, Soochow University;College of Life Sciences, Yanan University;

【Abstract】

<正>Toll-like receptors (TLRs) are well-known as patternrecognition receptors in the immune system for recognizing pathogen-associated and damage-associated molecular patterns [1]. TLRs play an essential role in the innate and adaptive immune responses. To date, 10 functional TLRs have been identified in humans (TLR1–TLR10) and 12 in

【Keywords】

TLR;MicroRNA21 Meets Neuronal TLR8;Non-canonical Functions of MicroRNA in Neuropathic Pain;

References

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Springer Journals Database

Total: 4 articles

  • [1] Tong Liu1, Yong-Jing Gao1,2, Ru-Rong Ji1 1 Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA 2 Institute of Nautical Medicine, Nantong University, Nantong 226001, China, Emerging role of Toll-like receptors in the control of pain and itch, Neuroscience Bulletin,
  • [2] Makoto Tsuda;Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University;Department of Molecular and System Pharmacology,Graduate School of Pharmaceutical Sciences, Kyushu University;, Modulation of Pain and Itch by Spinal Glia, Neuroscience Bulletin,
  • [3] Chul-Kyu Park;;Zhen-Zhong Xu;;Temugin Berta;;Qingjian Han;;Gang Chen;;Xing-Jun Liu;;Ru-Rong Ji, Extracellular microRNAs activate nociceptor neurons to elicit pain via TLR7 and TRPA1, Neuron,
  • [4] Qingjian Han;;Di Liu;;Marino Convertino;;Zilong Wang;;Changyu Jiang;;Yong Ho Kim;;Xin Luo;;Xin Zhang;;Andrea Nackley;;Nikolay V. Dokholyan;;Ru-Rong Ji, miRNA-711 Binds and Activates TRPA1 Extracellularly to Evoke Acute and Chronic Pruritus, Neuron,

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