GUO Li-li;ZHAO You-you;HUA Jin;MA Jing-jing;WANG Xiao-min;QIN Nan
Shanxi University of Chinese Medicine;Technology Center of Taiyuan Customs;Technology Center of Taiyuan Customs;Shanxi University of Chinese Medicine;Shanxi University of Chinese Medicine;Shanxi University of Chinese Medicine
Objective: To analyze the pesticide residues of Radix Polygalae and Radix Puerariae from different habitats and their extract from different batches with the method of SinChERS combined with LC-MS, which was established to detect 15 pesticide residues in Chinese herbal medicines. Methods: The samples were extracted and purified by SinChERS column and the pesticides residues of Radix Polygalae and Radix Puerariae from different origins and their extract from different batches were determined by LC-MS. Results: The linearity of 15 pesticides in the range of 2–200 ng/mL was good. The detection limits were 0.030–0.730 μg/kg with the quantification limits of 0.09–2.18 μg/kg, and the sample recoveries were 70.665%–119.400%. The pesticide residues in different origins of medicinal materials and different batches of extract were evaluated and there was no risk of use. However, the three pesticides with high toxicity including carbofuran, isazofos and ethoprophos, which were explicitly banned to be used in the Chinese herbal medicines, were detected. Conclusion: It is necessary to strengthen the supervision of Radix Polygalae and Radix Puerariae, and formulate and issue the corresponding pesticide residue and limit standards to standardize the market.
SinChERS combined with LC-MS;Pesticide residues;Medicinal materials;Radix Polygalae;Radix Puerariae
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