Xing-qi Yan1, Kang Tu2,3, Lu Xie3, Yi-xue Li2,3, Bin Yin1, Yan-hua Gong1, Jian-gang Yuan1, Bo-qin Qiang1, and Xiao-zhong Peng1 1National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005 2Bioinformatics Center, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031 3Shanghai Center for Bioinformation Technology, Shanghai 200235
Objective To provide a set of useful analysis tools for the researchers to explore the microRNA data. Methods The R language was used for generating the Graphical Users Interface and implementing most functions. Some Practical Extraction and Report Language (Perl) scripts were used for parsing source files. Results We developed a graphical R package named miRE, which was designated for the analysis of microRNA functions, genomic organization, etc. This package provided effective and convenient tools for molecular biologists to deal with routine analyses in microRNA-related research. With its help, the users would be able to build a desktop- centered microRNA research environment quite easily and effectively. miRE is freely available at http://www. biosino.org/~kanghu/WorkPresentation/miRE/miRE.html. A detailed user manual and tutorials with example code and image are also available. Conclusion miRE is a tool providing an open-source, user-friendly, integrated interface for microRNA-related analysis. With its help, researchers can perform microRNA-related analysis more efficiently.
microRNA; mRNA; expression profiles
To explore the background and basis of the node document