Rosuvastatin, A New HMG-CoA Reductase Inhibitor, Reduces Intestinal Ischemia-Reperfusion Mucosal Injury in Rats

【Author】

Takagi T.;Naito Y.;Ichikawa H.;Katada K.;Kuroda M.;Tsuboi H.;Handa O.;Kokura S.;Yoshida N.;Yoshikawa T.;

【Abstract】

<正> Inhibitors of HMG-CoA reductase are potent cholesterol -lowering drugs. However, accumulated evidence suggests that stains not only act by lowering cholesterol levels, but also exert pleiotropic effects on many essential functions including anti-inflammatory potents. In the present study, we investigated the effect of Rosuvastatin, a new HMG-CoA reductase inhibitor, in the development of the intestinal ischemia-reperfusion mucosal injury in rats.

【Keywords】

HMG;A New HMG-CoA Reductase Inhibitor;Reduces Intestinal Ischemia-Reperfusion Mucosal Injury in Rats;Rosuvastatin;

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